Wheat is one of the most commonly recognised environmental triggers. It contains proteins collectively known as gluten (also found in rye and barley), as well as other substances (such as wheat germ agglutinins or wheat lectins in the kernel that are meant to protect the plant from predators), which can cause inflammation, create imbalance in the gut microbiome (dysbiosis) and trigger a widespread immune response.

Experts agree that gluten and bad gut bacteria are the most powerful triggers of intestinal permeability or the ‘leaky gut’ (gaps in the gut lining). Additionally, research indicates that wheat remains undigested in many individuals due to a lack of necessary enzymes. Consequently, partially digested gluten proteins, known as peptides, may enter the bloodstream through the gaps, sparking systemic inflammation and alerting the immune system.

While some individuals appear unaffected by consuming gluten-containing grains, an increasing number of people are developing gluten sensitivity, also known as non-coeliac gluten sensitivity. As sensitivity emerges, the immune system might generate antibodies against various gluten peptides. Although scientific research has identified more than 36 gluten peptides, standard medical testing often focuses solely on alpha-gliadin antibodies. This immune response can lead to a phenomenon known as "molecular mimicry”, whereby certain gluten peptides or even pathogens (viruses or bacteria) share structural similarities with the body's tissues, such as the thyroid. Consequently, the immune system may produce auto-antibodies targeting these peptides and your tissues, triggering widespread inflammation. Over time, this immune response can potentially lead to the development of autoimmunity, especially if there is a genetic predisposition. 

Taking these factors into consideration, the initial step would involve undergoing specialised tests to determine if you possess sensitivities to various elements present in wheat or other gluten-containing grains and to identify the presence of a 'leaky gut' before fully embracing a gluten-free diet. However, if cost considerations come into play, transitioning to a gluten-free diet would still be a wise choice if you suspect or experience autoimmune conditions or unexplained chronic symptoms.

For those new to gluten-free living (which extends beyond mere dietary adjustments), the transition might appear daunting. However, you'll quickly discover that the benefits far surpass any initial challenges. Eliminating gluten from your diet can lead to swift improvements in your symptoms, if done correctly. As a Certified Gluten-Free Practitioner, I'm here to provide guidance, support and assistance throughout your journey, ensuring that you're well-equipped to navigate this transition successfully. Book your free 30-minute Exploratory Chat to discuss how I can help you on this path.